Human B7-H3 (4Ig) / B7-H3b Protein
| Specifications | |
|---|---|
| Category: | Immune Checkpoint Proteins |
| Molecular Weight: | 48.5 kDa |
| Tag: | C-10×His |
| Label / Conjugate: | N/A |
| Source: | Human B7-H3 (4Ig), His Tag (B7B-H52E7) is expressed from human 293 cells (HEK293). It contains AA Gly 27 - Thr 461 (Accession # Q5ZPR3-1). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | 4Ig-B7-H3,B7-H3,CD276,PSEC0249,UNQ309,PRO352,B7 homolog 3 |
| Organism: | Human |
| Accn. No.: | Q5ZPR3-1 |
Sequence Information
Gly 27 - Thr 461
Background
Human B7 homolog 3 (B7-H3) is a member of the B7 family of immune proteins that provide signals for the regulation of immune responses. Other family members include B7-1, B7-2, B7-H1/PD-L1, B7-H2, and PD-L2. B7 family proteins are type I transmembrane immunoglobulin (Ig) superfamily members that contain extracellular Ig V‑like and Ig C‑like domains with a short cytoplasmic tail. Termed 4IgB7-H3 or B7-H3b, this molecule has two additional Ig-like domains (one V‑type and one C‑type) and shows a ubiquituous expression pattern.
Price
442,00 €
