Biotinylated Cynomolgus B7-H7 / HHLA2 Protein, His,Avitag
| Specifications | |
|---|---|
| Category: | MABSol® Biotin Labeled Proteins |
| Molecular Weight: | 39.1 kDa |
| Tag: | C-10×His & C-Avi |
| Label / Conjugate: | Biotin-labeled |
| Source: | Biotinylated Cynomolgus B7-H7, His,Avitag (B77-C82E9) is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Asn 345 (Accession # XP_005548285.1). |
| Purity: | 90% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | B7-H7,HHLA2,B7 Homolog 7 |
| Organism: | Cynomolgus |
Sequence Information
Ile 21 - Asn 345
Background
B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
Price
1.839,00 €
