Human B7-H5 / Gi24 / VISTA Protein, Fc Tag
| Specifications | |
|---|---|
| Category: | Immune Checkpoint Proteins |
| Molecular Weight: | 44.8 kDa |
| Tag: | C-Fc |
| Label / Conjugate: | N/A |
| Source: | Human B7-H5, Fc Tag (B75-H5259) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 194 (Accession # AAH20568). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | B7-H5,SISP1,Gi24,VISTA |
| Organism: | Human |
| Accn. No.: | Q9H7M9-1 |
Sequence Information
Phe 33 - Ala 194
Background
Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
Price
365,00 €
