AAVPrime AAV Serotype Testing Kit Plus, 12 vials à 25 ul

Product Description

AAVPrime™ Adeno-associated virus (AAV) Serotype Testing Kit Plus (Cat. No. AA321) contains 12 premade GFP-expressing AAV in serotypes 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, DJ and DJ/8. All AAV particles are offered at 5 x 10¹¹ - 5 x 10¹² GC/ml, in 25 µl stocks, except serotypes 4 and 10 are offered at 5 x1011-1012 GC/ml. These kits are ideal for testing the infection efficiency of AAV serotypes in different cell types.

Figure 1. AAV of different serotypes carrying GFP were used to transduce HT1080 cell line at MOI 20,000 as shown in the figure above. Fluorescent images (GFP) show that cells are transduced with AAV-GFP.

Different serotypes differ mainly in surface protein (capsid). Carefully choosing the serotype enables robust gene expression in specific tissues with minimal immune response. Refer to the table below to compare the essential differences between different serotypes.

AAV Serotypes