Mouse/Rat FGF-acidic (FGF-1)
| Specifications | |
|---|---|
| Molecular Weight: | 15,9 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | Currently undetermined |
| Activity Assay: | Bioactive protein, but not acceptance criteria established |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, 75 mM Sodium Chloride, pH 7.5 |
Sequence Information
MFNLPLGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SAGEVYIKGT ETGQYLAMDT EGLLYGSQTP NEECLFLERL EENHYNTYTS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Background
Acidic fibroblast growth factor (aFGF), also known as FGF1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. aFGF regulates cardiogenesis through protein kinase C signaling. aFGF also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of aFGF are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of aFGF during T2DM.
- Catalog Number
800-10-10UG-SHE - Supplier
Fujifilm Irvine Scientific - Size
- Shipping
RT
Price
95,00 €
