Custom Selective Suppression Probes (SSPs)

Product Description

Highly-expressed RNA species reduce read depth of less abundant species that researchers care about. RealSeq Biosciences has developed a targeted removal probe (Selective Suppression Probe- SSP™) approach to depleting over-abundant species from RNA samples, resulting in increased miRNA reads and greater sequencing depth of miRNAs.

Figure 1. RealSeq Removal Probes deplete overabundant RNA sequences so that more sequencing space is dedicated to interesting sequences.

Figure 2. RealSeq Biosciences’ removal probes deplete RNA samples of highly-expressed RNA species and enhance reads of miRNAs. A panel of removal probes mixes were tested in triplicate with total RNA purified from human plasma.

SSPs improve miRNA Sequencing

RealSeq’s Selective Suppression Probe technology coupled with RealSeq Library prep enhances the miRNA reads you care about AND reduces your sequencing costs. We offer standard probes for human samples and customizable probes for your research needs. Contact us about your project to achieve high-quality results!