Accelerate the Understanding of Genome Structure & Sequence
Our partner Arima Genomics is a biotechnology company empowering researchers to apply long-range genetic sequence and structure information towards the understanding of health, disease and species evolution.
Arima-HiC technology is a proximity ligation method that captures the three-dimensional organizational structure and long-range gene regulatory interactions of chromatin, where genomic sequences that are closer to each other in the 3D space can be distal to each in linear distance - thereby preserving long range sequence and structure information prior to sequencing. Post-sequencing, this data can be used for multiple genomic applications including identification of promoter-enhancer interactions for gene regulation studies and Hi-C scaffolding of contigs for genome assemblies to define chromosomes de novo.