DNA methylation is the most widely studied epigenetic modification. DNA methylation occurs mainly on cytosine bases in the CpG dinucleotide motif in mammalian genomes, and across all cytosine contexts in plant genomes. DNA methylation is often associated with the regulation of gene expression through its presence or absence in CpG Islands among gene promoter regions, and these methylation patterns can be used to identify different cell types.
BioCat offers several kits for the preparation of bisulfit sequencing DNA and RNA libraries for Illumina platforms. The kits from our Partner EpigenTek are characterized by the following advantages: