Metabolism and Oxidative Stress Assays

Sensitive, Accurate and Straightforward

Metabolism Assays

Metabolism is a vital process for all life forms. It is broadly defined as the sum of all the biochemical processes involved in maintaining the living state of the cells, and thus the organism. Transformation of the macronutrients such as carbohydrates, proteins, and fats into energy is an integral part of the metabolic processes. They can be divided into two main categories: anabolic processes, which consume energy to synthesize simple molecules or polymerize them into more complex macromolecules, and catabolic processes that degrade molecules to release energy. Understanding the basic biological mechanisms that regulate metabolism and how they are dysregulated in disorders such as obesity, diabetes, stroke, and cancer is a crucial aspect of disease-oriented research.

To advance your metabolism research, a wide variety of sensitive, accurate, and straightforward assays and ELISA kits is offered.

• Cellular Metabolism
• Lipid Metabolism
• Carbohydrate Metabolism
• Amino Acid & Protein Metabolism
• Intermediary Metabolism

Oxidative Stress Assays

Oxidative stress is often defined as an imbalance of pro-oxidants and antioxidants. All forms of life maintain a reducing environment within their cells. This reducing environment is preserved by enzymes that maintain the reduced state though a constant input of metabolic energy. Disturbances in this normal redox state can cause toxic effects through the production of a number of reactive oxygen species (ROS) which the cell is unable to counterbalance. The result is damage to one or more biomolecules including DNA, RNA, proteins and lipids. Oxidative stress has been implicated in the natural aging process as well as a variety of disease states. ROS can also be beneficial, they are employed by the immune system as a way to attack and kill pathogens. In addition, they are involved in cell signaling. Selecting assays for analyzing oxidative stress begins with your samples. There are many markers of oxidative stress, but some are more easily detected in certain sample types (cells, tissues, urine, blood, etc.).

A broad portfolio of sensitive, easy-to-use assays to quantify oxidative stress is provided.

• DNA Damage
• Lipid Peroxidation
• Protein Oxidation
• Reactive Oxygen
• Species Antioxidants