Available only from SBI and featured in a recent Nature Communications article, our CLOuD9 Gene Expression Regulation Kit gives you an exciting and innovative tool for studying—and potentially controlling—gene expression regulation by putting you in control of chromatin loop formation. Gain a clearer understanding of the dynamic effects of chromatin restructuring on the expression of your gene-of-interest and increase gene expression in certain cellular contexts. Combining the simplicity of CRISPR/Cas9 targeting—free from DNA cleavage activity—with inducible and reversible protein dimerization partners, the CLOuD9 Gene Expression Regulation Kit adds a new dimension to your gene regulation studies.
Figure 1. The CLOuD9 System enables formation of inducible and reversible chromatin loops anywhere in the genome.