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Pinpoint FISH DNA Probes

Pinpoint FISH DNA Probes

Pinpoint FISH is a fully synthetic FISH technology based on single stranded fluorescently labeled DNA oligonucleotides.

Pinpoint FISH will run on standard cytogenetic systems, requires no special equipment, and produces data indistinguishable from BAC FISH. Standard Pinpoint FISH DNA Probes are available with 5 different fluorophores. Other fluorophores are available upon request. Please contact us for additional information.

  • 6-FAM / Spectrum Green
  • Atto425 / Aqua
  • Atto550 / Spectrum Orange
  • Atto643 / 647 / Cy5
  • TexRed

Pinpoint FISH vs BAC FISH

Pinpoint Fish Vs. Bac

Centromere Enumeration Probes (sub-CEPs)

Centromere Enumeration Probes (sub-CEPs) from KromaTiD are available for all human chromosomes as standard products.  KromaTiD sub-CEPs make use of pericentric non-repetitive genomic DNA to provide a uniform signal from chromosome to chromosome.

Telomeric Probes (sub-Telos)

Telomeric Probes (sub-Telos) from KromaTiD are available for the p- and q-arms of all human chromosomes as standard products, other sequenced species are available by request. KromaTiD sub-Telos make use of pericentric non-repetitive genomic DNA to provide a uniform signal from chromosome to chromosome.

Human Whole Chromosome Paints

Whole Chromosome Pinpoint FISH Paints from KromaTiD are available for all human chromosomes as standard products. KromaTiD Whole Chromosome Pinpoint FISH Paints make use of non-repetitive genomic DNA to provide a uniform signal from chromosome to chromosome. Two formats are available, high density (HD) and medium density (MD). KromaTiD HD paints are designed to cover all the unique genomic sequences in the genome and contain a high density of fluorescently labeled oligonucleotides. They provide more uniform fluorescence across the entire length of the target chromosome than MD paints. MD paints are designed with equal spacing of concentrated probe signals across the entire length of the chromosome. 

TP53/CEP 17 Kit

The Pinpoint FISH TP53/CEP 17 Probe Kit is intended to detect the copy number of the LSI TP53 probe target located at chromosome 17q11.1 and of the CEP 17 probe target located at the centromere of chromosome 17.

Pinpoint FISH Assay Service

Besides premade probes, also genome wide, custom Pinpoint FISH assays engineered to meet your specific requirements are offered. Using KromaTiD’s proprietary design approach, we provide assays optimized for detecting small targets, specific breakpoints or transgene inserts.