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Retrovirus Technology

Gamma-retroviral vectors for dividing-cell-only integration and legacy retrovirus workflows

When you specifically want dividing-cell-only integration or you have legacy retrovirus workflows, gamma-retroviral vectors (MMLV-derived) deliver it. Largely displaced by lentivirus in research applications but retained for specific use cases including some hematopoietic stem cell gene therapy.

Pick by backbone and envelope.

  1. Backbone. Third-generation safety standard for clinical-translatable work. Second-generation simpler for research.
  2. Envelope. VSV-G for broad tropism. Ecotropic for mouse-only safety.
  3. Use case. Legacy workflows, dividing-cell-only integration specifically. Otherwise lentivirus is the modern default.
  4. Titration. qPCR-based.

Cell Biolabs is the primary supplier in this catalogue.

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