Gamma-retroviral vectors for dividing-cell-only integration and legacy retrovirus workflows
When you specifically want dividing-cell-only integration or you have legacy retrovirus workflows, gamma-retroviral vectors (MMLV-derived) deliver it. Largely displaced by lentivirus in research applications but retained for specific use cases including some hematopoietic stem cell gene therapy.
Pick by backbone and envelope.
- Backbone. Third-generation safety standard for clinical-translatable work. Second-generation simpler for research.
- Envelope. VSV-G for broad tropism. Ecotropic for mouse-only safety.
- Use case. Legacy workflows, dividing-cell-only integration specifically. Otherwise lentivirus is the modern default.
- Titration. qPCR-based.
Cell Biolabs is the primary supplier in this catalogue.