Purified Nucleosomes (HeLa, Avian)

Purified native nucleosomes from HeLa and avian erythrocyte nuclei for chromatin studies

When you need physiologically heterogeneous chromatin substrates rather than defined recombinant nucleosomes, native nucleosomes purified from HeLa or avian erythrocyte nuclei retain the full diversity of native modifications. Useful for chromatin biochemistry, ChIP controls, and assay development.

Pick by source and use case.

1. Source. HeLa nucleosomes for human-derived studies. Avian erythrocyte nucleosomes for tightly packed substrates good for in vitro chromatin assembly.
2. Use case. For mechanistic enzyme studies recombinant defined nucleosomes outperform. Reserve native for context-dependent biology or assay-development controls.
3. Preparation grade. Research-grade versus assay-validated. Published validation matters for downstream interpretation.
4. Storage. Verify storage stability.

EpiCypher supplies purified native nucleosomes.