Adenovirus Technology

Adenovirus vectors for high-titre transient gene delivery to primary cells and tissue

When you need high-titre transient gene delivery, especially to primary cells and tissue, adenovirus vectors deliver higher transduction efficiency than lentivirus or AAV in many cell types. Supports large payload sizes up to 8 kb first-generation and up to 36 kb helper-dependent.

Pick by serotype and purity.

1. Serotype. Ad5 standard. Alternative serotypes for retargeting or immune evasion.
2. Payload size. Up to 8 kb first-generation. Up to 36 kb helper-dependent.
3. Purity grade. For in vivo use iodixanol-gradient purification to minimise endotoxin and reduce inflammatory responses.
4. Use case. In vivo gene delivery research, vaccine development, oncology translational work.
5. Titration. qPCR-based; UV overestimates.

Cell Biolabs leads adenovirus titration and characterisation tools. Norgen Biotek supplies isolation and purification reagents.