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3D Hydrogel Systems

Natural, synthetic, and hybrid 3D hydrogel systems with tunable stiffness and degradation

When 2D plastic stops modelling the biology you care about, 3D hydrogels suspend cells in a polymer scaffold with tunable stiffness, biofunctionalisation, and degradation. The category includes natural matrices (collagen, fibrin, hyaluronic acid, Matrigel) with native ECM cues, synthetic PEG-based hydrogels with defined chemistry, and hybrid formulations.

Pick by reproducibility and physiological context.

  1. Reproducibility-critical work. Choose defined synthetic hydrogels (TheWell VitroGel, Cellendes 3D Life). Tunable stiffness, defined biofunctionalisation, predictable batch-to-batch.
  2. Native ECM context. Choose natural matrices (collagen, Matrigel). Accept higher lot variance for native cues.
  3. Stiffness. Match kPa to native tissue. Soft for brain or liver, stiffer for cartilage or bone.
  4. Cell-friendly gelation. Photo-, temperature-, ion-, or click-crosslinked chemistries differ in cell viability during gelation. Match to your cell type.
  5. Imaging compatibility. Confirm clearing-protocol compatibility before committing.

TheWell supplies VitroGel in this inventory.

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Reach our team for quotes, order status, shipping questions, or anything else related to working with BioCat. We typically respond within one business day.

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